SCIENCE & EVIDENCE

OKCLEAR Evidence

Understand the pathway, examine the evidence boundaries

OKCLEAR separates published science, product-specific testing and commercial statements so each type of conclusion can be assessed against its own evidence.

PUBLIC RESEARCH

Published research background

The published studies below explain the scientific background for cat allergens and the IgY route. Unless stated otherwise, they are not OKCLEAR finished-product test results.

105cats

IID · 2019

Active Fel d 1 on the coat

Significant reduction from week 3; an average reduction of about 47% later in the study

View DOI ↗

26weeks

Frontiers · 2020

Adult cat safety

No ingredient-related adverse effects observed under the test conditions

View DOI ↗

84days

Frontiers · 2024

Kitten safety

27 kittens in a randomized blinded controlled study; no biologically meaningful adverse changes

View DOI ↗

42people

MASK-air · 2024

Human home observation

After one month, overall, nasal, ocular and symptom–medication scores all showed improvement

View DOI ↗

Different products and published studies may use different samples, assays, time points and endpoints, so no head-to-head superiority comparison is made. Conclusions depend on the applicable SKU and evidence materials.

SCIENCE & EVIDENCE

Evidence pathway

OKCLEAR separates published science, product-specific testing and commercial statements so each type of conclusion can be assessed against its own evidence.

MECHANISM

Specific IgY binds Fel d 1

Published research validates the molecular mechanism of source-side management with egg-yolk antibodies.

CAT STUDIES

Active Fel d 1 falls in saliva and on the coat

In a 105-cat study, significant change appeared from week 3, with an average reduction of about 47% later in the study.

HUMAN HOME STUDY

Multiple symptom scores improved after one month

The 2024 MASK-air study recorded changes in overall, nasal, ocular, asthma and symptom–medication scores.

EPITOPE ENGINEERING

2026 study: 23 cats, 4 weeks

Salivary Fel d 1 fell by about 50%–71% in some dose groups, showing the R&D potential of multi-epitope antigens and specific IgY.

SAFETY

Use and safety boundaries

  • OKCLEAR products do not diagnose, prevent or treat human allergic disease, and they do not make a cat allergen-free.
  • Published results come from specific formulations, doses and test conditions; they are not automatically results for an OKCLEAR finished product.
  • Product indicator conclusions depend on the applicable SKU, batch, sample, assay, time point and test condition.
  • Seek urgent medical care for breathing difficulty, blue lips or face, severe wheezing, or rapidly worsening throat symptoms.

RESEARCH BACKGROUND

Started by a team with a Zhejiang University pet-nutrition research background

This statement describes the team’s research background. It does not mean OKCLEAR is an official Zhejiang University product, produced by the university, or officially endorsed by it.

PUBLIC RESEARCH

Request technical materials

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